Scientific Name: Rattus norvegicus
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Muridae-> Murinae
Summary: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] [NCBI] [Proteinatlas]
Data set information
| Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
|---|---|---|---|---|---|---|
| Vthunter_1001 | 2019.12 | 10X Genomics | Lung | Normal | 5029 | Link |
| Vthunter_1002 | 2019.12 | 10X Genomics | Lung | Normal | 5924 | Link |
| Vthunter_1009 | 2017.11 | Fluidigm C1 | UrogenitalSinus | Normal | 114 | Link |
| Vthunter_110073 | 2019.12 | MARS-seq | TotalBrain | Normal | 2304 | Link |
Featureplot of receptors
Expression: Ubiquitous expression in placenta (RPKM 24.8), testis (RPKM 23.6) and 25 other tissues
